Thermography for Breast Cancer Detection

The use of body temperature to diagnose disease dates back to 480 B.C. when Hippocrates wrote about spreading mud on his patients, suspecting the areas that dried first might indicate possible problems in underlying organs. Since then, technological progress has made thermography, a modern technique for measuring body temperature, possible.

Thermography has been studied for its usefulness in breast cancer detection since 1956 and the United States Food and Drug Administration approved it as an adjunctive screening tool in 1982. The popularity of screening mammography caused thermography to fall out of favor, but recent revelations about the limitations and adverse effects of mammograms has renewed interested in this promising alternative.

The Difference

While mammograms measure anatomy, thermograms measure physiology. Mammography uses compression and ionizing radiation to take pictures of breast tissue, making the procedure painful and increasing the risk of developing cancer. Thermography is a painless test that uses infrared imaging to detect heat patterns on the surface of the skin related to inflammation, blood flow and angiogenesis, the formation of new blood vessels. Angiogenesis is a critical step in the growth of cancer because as abnormal cells increase in number, so do their requirements for oxygen and nutrients, the food needed to fuel proliferation. To meet their expanding needs, tumors generate new vessels to increase blood flow, and this in turn increases skin temperature.

Earlier Detection

Because inflammatory and vascular changes related to cancer growth can be detected sooner than solid tumors, which may take years to grow large enough to block x-ray beams and be identified on mammograms, thermograms can identify signs of malignancy in its earliest stages. Some experts estimate that thermography recognizes cancerous or pre-cancerous changes up to ten years earlier than any other procedure, mammography included.

Because earlier detection can lead to earlier treatment and improved prognosis, thermograms offer significant survival benefits. A study published in the American Journal of Obstetrics and Gynecology followed almost 500 women diagnosed with breast cancer for five years. Only one of the two groups was screened with thermography. For these women, thermograms tested positive (abnormal), finding malignant cells before physical breast exams and mammograms, which tested negative (normal), could detect them. Both groups were given identical treatment and, after five years, the women whose cancer was detected by thermography lived longer. Screening thermograms increased survival by 61 percent.

Increased Accuracy

Another distinguishing difference between thermography and mammography is its accuracy. Mammograms correctly diagnose cancer only three percent of the time, according to a Harvard study published in the New England Journal of Medicine. In contrast, studies have shown that thermograms are highly sensitive and specific. (Sensitivity is the percentage of accurate positive results and specificity is percentage of accurate negative results.) A review of 15 large-scale studies published in the International Journal of Thermal Sciences concluded that breast thermography had an average sensitivity and specificity of 90 percent. Some studies have found sensitivity as high as 98 percent and specificity as high as 94 percent. With false positive rates of 10 percent on average, and as low as two percent, thermography is significantly more accurate than mammography, which has false positive rates as high as 97 percent.

Thermograms are notably more accurate in individuals who have large breasts, because excessive amounts of tissue can make mammograms difficult to read, and those who have dense breasts, common in younger women. For those who have a higher risk of developing breast cancer, thermography makes starting screening at earlier ages not only safer, but also much more effective.

The Bottom Line

Research has shown that abnormal thermograms are the most important indicators in predicting the development and recurrence of breast cancer. Experts even estimate that they are up to 10 times more significant than family history (having a mother, sister or daughter diagnosed with the disease). Because thermograms are painless, noninvasive, reliable and free of side effects, this alternative to screening mammography should be made available to all women.

References

Fletcher SW and Elmore JG. Mammographic Screening for Breast Cancer. New England Journal of Medicine, 348(17):1672-1680, 24 Apr 2003.

Gautherie M. Thermobiological assessment of benign and malignant breast diseases. American Journal of Obstetrics and Gynecology, 147(8):861-9, 15 Dec 1983.

Gros C and Gautherie M. Breast Thermography and Cancer Risk Prediction. Cancer, 45:51-56, 1980.

Haberman J. The present status of mammary thermography. CA: A Cancer Journal for Clinicians, 18: 314-321,1968.

Louis K, Walter J and Gautherie M. Long-term assessment of breast cancer risk by thermal imaging, Biomedical Thermology, Alan R. Liss, Inc. pp. 279-301, 1982.

Ng EY-K. A review of thermography as promising non-invasive detection modality for breast tumor. International Journal of Thermal Sciences, 48(5):849-859, May 2009.

Ng EY et al. Computerized detection of breast cancer with artificial intelligence and thermograms. Journal of Medical Engineering and Technology, 26(4):152-7, Jul-Aug 2002.

Stark  A and Way S. The Screening of Well Women for the Early Detection of Breast Cancer Using Clinical Examination with Thermography and Mammography. Cancer, 33:1671-1679, 1974.

Mammograms Misunderstood

The United States Preventive Services Task Force recently changed their recommendations regarding screening mammography. After a thorough review of the research, this independent panel of experts appointed by the Department of Health and Human Services concluded that most women should be tested every two years between the ages of 50 and 74, replacing previous recommendations for yearly lifelong tests starting at age 40.

The new guidelines have been met with confusion and outrage. Critics have dismissed them as a cost-cutting measure and described them as “a giant step backward.” The new recommendations have been called “deadly for women” and even “gendercide.” Although they could save billions of dollars in unnecessary testing and treatment, the financial savings are only a bonus. The new guidelines really are good for women and a review of the literature can quickly clear up the controversy.

Zero Benefit

In 2001 the benefits of screening mammography underwent serious scrutiny by the well-respected Cochrane Collaboration, an international, independent, not-for-profit research organization. They performed an objective and systematic review of the seven largest screening mammography studies ever done and examined the effects in a half million women from the United States, the United Kingdom, Canada and Sweden.

Two of the seven studies met the gold standard for research: randomized controlled trials. They followed 130,000 women for 13 years and compared women who received regular mammograms to those who did not. Researchers found that the rate of death from breast cancer, and from any other cause, was the same in both groups. When all seven studies were considered, mammograms were still not associated with a statistically significant reduction in the risk of death. Surprising as these studies are, the results are clear: screening mammography does not save lives.

False Positives

Mammograms are positive when abnormal tissue is detected. False positive tests occur when mammograms mistakenly identify cancer in normal tissue. A 2005 review of randomized controlled trials published in the Journal of the American Medical Association found that 95 percent of positive mammography results are false. A Harvard study published in the New England Journal of Medicine found that only three percent of abnormal mammography results were valid, making the frequency of failure 97 percent.

False positive results can be a grave matter. A study published in the Annals of Internal Medicine found that 47 percent of women with high-suspicion mammograms experience substantial anxiety. While most women are relieved to learn that their test results were wrong and they do not have cancer, many suffer unnecessary emotional turmoil.

Harmful Effects

Screening mammography can have other harmful effects. Women with false positive results are needlessly subjected to biopsies, lumpectomies and associated adverse effects, including pain, infection and scarring. Those with true positive results are too often treated for cancers that would have otherwise gone unnoticed. A 2009 study published in the British Medical Journal concluded that one out of every three breast cancers identified on screening mammograms is overdiagnosed and would not cause symptoms or death. The surgery, chemotherapy and radiation used to treat these tumors are always harmful. Side effects and complications can include mouth sores; fatigue; vomiting; digestive problems; skin rashes; hair loss; damage to peripheral nerves; changes in brain function affecting memory, concentration and learning; premature menopause; leukemia (cancer of the blood); and death.

Ionizing radiation from mammograms is another valid concern. It can damage genetic material in cells and cause cancerous mutations. These tests are used to find cancer, but taking too many of them can also cause cancer. This detail has been overlooked in the past because the benefits of mammograms – saving lives – were thought to outweigh the harmful effects. But for most women, screening mammography does not save lives and the risks associated with radiation can no longer be ignored. There is a direct relationship between cumulative exposure to radiation and the risk of cancer, so the more mammograms (and other procedures involving ionizing radiation like CT scans) that women receive over their lifetimes, the more likely they are to develop cancer.

Some Exceptions

Screening mammography may not reduce the risk of death for most women, but for certain women, the benefits can outweigh the dangers. Women who have the highest risk for developing breast cancer have the most to gain from screening tests. These include women with two first-degree relatives (mother, daughter, sister) or second-degree relatives (aunt, grandmother) diagnosed with breast cancer before the age of 50; women who have three first- or second-degree relatives with breast cancer diagnosed at any age; individuals with a history of chest radiation between the ages of 10 and 30; and those who have a known gene mutation linked to breast cancer. These individuals should talk to their doctor about the best screening schedule for them.

Diagnostic mammograms are another exception. Unlike screening mammography, which is performed on healthy women, diagnostic mammography is used to evaluate known breast problems. For women with lumps, tissue abnormalities, nipple discharge or a history of cancer, these tests can provide life-saving information for diagnosis and treatment.

Accurate Alternative

Thermography is a promising alternative to mammography. This infrared imaging technique is painless, non-invasive and free of radiation. It measures heat patterns on the surface of the skin related to blood flow and angiogenesis, the formation of new blood vessels. Angiogenesis is a critical step in the growth of cancer because as abnormal cells increase in number, so do their requirements for oxygen and nutrients, the food needed to fuel proliferation. To meet their expanding needs, tumors generate new blood vessels to increase blood flow, which increases skin temperature.

Because these vascular changes can be detected sooner than solid tumors, which may take years to grow large enough to block x-ray beams and be identified on mammograms, thermograms can identify signs of cancer in its earliest stages. Some experts estimate that thermography recognizes cancerous or pre-cancerous changes up to 10 years earlier than any other procedure, mammography included.

Studies have shown that thermograms are also much more accurate than mammograms. A review of 15 large-scale studies published in the International Journal of Thermal Sciences concluded that breast thermography had an average sensitivity and specificity of 90 percent. (Sensitivity is the percentage of accurate positive results and specificity is percentage of accurate negative results.) Other studies have found sensitivity as high as 98 percent and specificity as high as 94 percent. With rates of false positive and false negative results averaging only 10 percent, thermography is an accurate alternative to mammography.

The Bottom Line

Like any medical procedure, the pros and cons of mammograms must be considered carefully. Given the frequently false positive results, lack of benefit and exposure to radiation, screening mammography is not an effective tool for detecting breast cancer in the general population. For most women, preventive measures are much more beneficial: exercising regularly, maintaining an ideal weight, breastfeeding, avoiding pesticides and eating a healthy diet that includes seven or more daily servings of fruits and vegetables, especially cruciferous and dark green leafy vegetables.

REFERENCES

Elmore JG, Fletcher SW et al. Screening for breast cancer. Journal of the American Medical Association, 293(10):1245-56, 9 Mar 2005.

Fletcher SW and Elmore JG. Mammographic Screening for Breast Cancer. New England Journal of Medicine, 348(17):1672-1680, 24 Apr 2003.

Gøtzsche PC, Nielsen M. Screening for breast cancer with mammography. Cochrane Database of Systematic Reviews 2009, Issue 4. Art. No.: CD001877. DOI: 10.1002/14651858.CD001877.pub3.

Griffey RT and Sodickson A. Cumulative radiation exposure and cancer risk estimates in emergency department patients undergoing repeat or multiple CT. American Journal of Roentgenology, 192(4):887-92, Apr 2009.

Haberman J. The present status of mammary thermography. CA: A Cancer Journal for Clinicians, 18: 314-321,1968.

Jorgensen KJ and Gøtzsche PC. Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends. British Medical Journal, 339:b2587, 9 July 2009.

Lerman C et al. Psychological and behavioral implications of abnormal mammograms. Annals of Internal Medicine, 114(8):657-61, 15 Apr 1991.

Nelson HD et al. Screening for breast cancer: an update for the U.S. Preventive Services Task Force. Annals of Internal Medicine, 151(10):727-37, W237-42, 17 Nov 2009.

Ng EY-K. A review of thermography as promising non-invasive detection modality for breast tumor. International Journal of Thermal Sciences, 48(5):849-859, May 2009. DOI:10.1016/j.ijthermalsci.2008.06.015.

Ng EY et al. Computerized detection of breast cancer with artificial intelligence and thermograms. Journal of Medical Engineering & Technology, 26(4):152-7, Jul-Aug 2002.

Stark A and Way S. The Screening of Well Women for the Early Detection of Breast Cancer Using Clinical Examination with Thermography and Mammography. Cancer 33:1671-1679, 1974.

Urban Composting

According to the Lower East Side Ecology Center, the Department of Sanitation in New York City collects 13,000 tons of garbage everyday, and almost 5,000 tons – close to forty percent – account for organic materials that could be composted. Composting not only reduces waste, it also saves greenhouse gas emissions from refuse transport and provides nutrient-rich plant food for gardens, yards and parks. Because the health of the planet plays an important role in our own health, composting is something to be taken seriously and everyone can participate. Many urbanites wouldn’t consider composting compatible with city life, but surprisingly, it is.

Get Started

Worm bin composting requires few materials, little maintenance and less than three cubic feet of space. Properly managed, worm bins are discrete and odorless, and they do not attract pests. Bins can be tucked away inside a closet or pantry, under the kitchen sink, or in any shady spot, as long as the air vents are unobstructed and the temperature remains between 50 and 80 degrees Fahrenheit. A standard size bin, sometimes called a Worm Condo, usually measures 12 by 16 by 19 inches, but any lidded plastic container of similar size, with air holes and drainage holes, will work well.

To set up a worm bin, begin with bedding materials referred to as “greens” and “browns.” Greens are organic materials rich in nitrogen. These can include fruit and vegetable scraps, coffee grounds, coffee filters, tea leaves, tea bags and fresh green plant materials like wilted flower bouquets, weeds and grass clippings. Browns are rich in carbon. These include newspaper, office paper (nothing shiny), paper bags, cardboard, food-soiled napkins and paper towels, dryer lint, saw dust, wood shavings, egg shells, corn cobs, stale bread and dry plant material like fall leaves, dead pine needles and dried flowers.

Place up to three pounds of green materials in one corner of the bin. Shred some newspaper into one-inch strips (you will need about five newspapers if this is the only brown material you plan to use). Dip them in water and squeeze out as much moisture as possible. Separate the strips and drop them into the bin, along with any other browns, on top of the greens. Fill the container up to the bottom of the air vents, roughly three inches from the top. All of the greens should be covered by browns. The browns should have a fluffy appearance and allow for plenty of air circulation, creating a humid, but not wet, environment.

On top of the browns, add one pound of Red Wigglers – approximately 1,000 worms – and cover the container tightly. Ensure that the air vents at the top are open and unobstructed. There should be little drainage, but a small amount is normal, so place the bin on a tray lined with an old towel or newspaper to absorb any liquid.

To maintain the worm bin, place up to three pounds of greens in the bottom of the bin each week (a volume approximately equivalent to a standard size bread bag). Imagine that the bottom of your bin is divided into six equal areas and use one area each week. Rotate your disposals around the bin, returning to the first area six weeks later. Each time you add greens, be sure to place them at the bottom and cover them with browns.

After approximately four months, the bedding will begin to resemble crumbly black dirt and the compost will be ready to harvest. Move everything to one side of the bin and stop adding greens to this compost. On the empty side, add new greens and browns and continue composting.

Two weeks later, most of the worms should have moved over to the new bedding. Remove the compost and redistribute the browns to the empty side of the bin, adding more if necessary. Use the compost you harvested to feed plants, trees or grass. If you can’t use all of the compost yourself, donate it to local farms or community gardens.

Follow Four Rules

To avoid odors and infestations, follow four simple rules. First, maintain roughly equal amounts of greens and browns inside your bin, but always add slightly more browns. Greens are typically damp materials, and if there are too many, the environment will become too wet and foster microbial growth. If this happens, add more browns, which are typically dry materials, to absorb excess moisture.

Second, refrain from adding oily foods to your worm bin. This includes salad dressings, sauces, meat and fish scraps, cheese and other dairy products. Because fats and oils turn rancid more quickly at room temperature, they can become smelly.

Third, avoid adding the skins and peels of citrus and tropical fruits to your worm bin, or treat them first. Fruit flies often lay eggs on these fruits, and eggs that hatch inside a worm bin can quickly create an infestation. To kill any fruit fly eggs before they can hatch, freeze citrus peels and tropical fruit skins overnight or heat them for one minute in the microwave (and cool to room temperature) before adding them to your worm bin.

Fourth, avoid adding anything to the bin that might threaten the health of your worms and their ecosystem. This includes pet waste, diseased plants, pesticide-treated plant materials, pressure-treated lumber, glossy paper, charcoal, weeds with seeds, invasive weeds, dead animals, and inorganic materials like plastic, metal and glass.

Learn More

The Lower East Side Ecology Center in New York City offers informative workshops like Worm Composting 101, a Children’s Wormshop, and Worm Composting for the Classroom, designed for teachers who want to start class projects. They sell materials, including Worm Condos and the Red Wigglers that love them, and accept donations of organic materials for composting (approximately 1,000 households currently donate six tons per week). The Center also offers a free composting hotline to answer questions and help troubleshoot problems (212-477-3155).

Visit their website at www.lesecologycenter.org or stop by their stand at the Union Square Greenmarket any day it is open (8 to 5 every Monday, Wednesday, Friday and Saturday) to get more information, register for a class, donate your organic waste, or buy some authentic New York City compost.

Preventing Swine Flu

The upper respiratory infection caused by the H1N1 influenza virus, commonly called the swine flu, has everyone on alert. Preliminary reports suggest that most cases are limited to mild illness and unless the virus mutates or combines with a more dangerous virus, an above-average incidence of death and disability are unlikely. Immunization efforts are underway but swine flu vaccines have sparked controversy and concern over questionable ingredients and inadequate safety information. My patients frequently ask me to make recommendations for alternatives to vaccination, so here I share some simple strategies to enhance immunity and prevent infection during swine flu season.

Common Sense


The swine flu is much like the regular flu. The symptoms are similar – fatigue, fever, chills, sore throat, cough, runny nose, headache, body aches – and like other influenza viruses, H1N1 is transmitted through contact with respiratory secretions of infected individuals, usually after coughing, sneezing or touching common surfaces. To prevent transmission, avoid touching your mouth, nose, or eyes and wash your hands often with hot, soapy water and lots of friction, for at least twenty seconds. Although people can become contagious before symptoms even start, use your best judgment and avoid contact with individuals who appear to be sick. If you are ill, stay home to prevent spreading the infection to others.

Good Nutrition

While a multiple vitamin-mineral supplement can provide the nutrients necessary for a healthy immune system, it is no substitute for whole foods. Eat a wide variety of fruits, vegetables, whole grains, beans, raw nuts and seeds. If you eat meat, choose pasture-raised and grass-fed animals. If you eat seafood, choose small fish that live in cold water, like anchovies, sardines, herring and wild salmon, and avoid large fish at the top of the food chain, like tuna and swordfish. Avoid processed foods, trans-fats, hydrogenated oils, refined carbohydrates like white flour and sugar, and excessive intake of alcohol. Unless you have kidney disease or your doctor has told you otherwise, drink plenty of fluids. The best choices are filtered or spring water and unsweetened herbal or green tea.

Sufficient Sleep

Getting enough sleep is important for a healthy immune system. A study published in the Archives of Internal Medicine found that healthy adults who slept at least eight hours each night had a higher resistance to upper respiratory infections. Participants reported their sleep duration and sleep efficiency (time spent in bed asleep) every night for two weeks before they were exposed to a rhinovirus known to cause the common cold. Those who reported less than seven hours of sleep per night were almost three times as likely to develop a cold than those who slept eight hours or more. Participants who reported poor sleep efficiency (less than 92 percent) were five and a half times more likely to come down with a cold compared to those who reported a high sleep efficiency (98 percent or above). Although this study focused on rhinoviruses, sufficient sleep is most likely an essential element in preventing other upper respiratory infections, like swine flu, as well.

Regular Exercise

Exercise can also impact immunity. One study, published in the American Journal of Medicine, followed 115 sedentary postmenopausal women for one year to study the effects of physical activity on resistance to upper respiratory infections. Participants were divided into two groups: one exercised for 45 minutes at a moderate intensity, five days each week, while the other attended one 45-minute stretching session, one day per week. Researchers concluded that the stretchers had a much greater risk of getting sick than the exercisers, by a factor of three in the final three months of the study. If regular exercise can increase resistance to upper respiratory infections in older women, there is a good chance it can be helpful for the prevention of swine flu in others.

Vitamin D

Studies have shown that vitamin D can stimulate the production of white blood cells responsible for identifying and destroying abnormal cells, like the H1N1 virus, and producing anti-microbial peptides that protect the respiratory system from infection. Studies have also shown that low blood levels of vitamin D are associated with an increased incidence to colds and flu. Vitamin D production is stimulated in the skin upon exposure to ultraviolet radiation and levels may be low during colder months when we spend less time in the sun. Blood levels of Vitamin D can be tested by your doctor and should ideally fall between 60 and 90 nanograms per milliliter (ng/ml). If levels are low, vitamin D can be taken in supplement form to increase immunity during cold and flu season.

Probiotics

Probiotics are healthy bacteria that normally live on our bodies and inside our gastrointestinal tracts. These supplements are most commonly used to treat digestive disorders but studies show that probiotics can also play an important role in respiratory tract infections. In a double-blind, placebo-controlled study published in Pediatrics, researchers followed 326 healthy children between the ages of three and five years taking a placebo or probiotic product (lactobacillus acidophilus alone or in combination with bifidobacterium) twice daily for six months. Compared to placebo, the kids who took probiotics experienced fewer cold- and influenza-like symptoms, including fever, cough and runny nose, and they recovered faster when they did get sick. They reported less illness-related school absences and required fewer prescriptions for antibiotics. If probiotic supplements can be protective against the flu, they may be useful in preventing the swine flu as well.

Botanical Medicines

Elderberry has a long tradition of use as treatment for upper respiratory infections and a recent study, published in Phytochemistry, supports its efficacy against the H1N1 virus. Researchers found that elderberry flavonoids can bind the H1N1 virus and block its ability to infect host cells. They concluded that its anti-viral activity is comparable to pharmaceuticals Oseltamivir (Tamiflu) and Amantadine.

Other herbal medicines used to prevent and treat viral upper respiratory infections include Astragalus root and medicinal mushrooms like reishi, shiitake and maitake. These botanicals have been used in traditional Chinese for thousands of years as restorative tonics, immune stimulants, and adaptogenic herbs that increase resistance to stress and illness.

Good Guidance

Like pharmaceutical medications, nutritional and herbal supplements are not appropriate for everyone. Before taking anything new, talk to a doctor trained in the use of natural medicines about contraindications, side effects, potential interactions, and the best dosage for you.

REFERENCES

Cannell JJ et al. Epidemic influenza and vitamin D. Epidemiol Infect. 2006 Dec;134(6):1129-40.

Chubak J et al. Moderate-intensity exercise reduces the incidence of colds among postmenopausal women. Am J Med. 2006 Nov;119(11):937-42.

Cohen S et al. Sleep habits and susceptibility to the common cold. Arch Intern Med. 2009 Jan 12;169(1):62-7.

Leyer GJ et al. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics. 2009 Aug;124(2):e172-9.

Roschek B Jr et. al. Elderberry flavonoids bind to and prevent H1N1 infection in vitro. Phytochemistry. 2009 Jul;70(10):1255-61.

Improving and Protecting Memory

Memory is a complicated neurological process and our understanding has progressed rapidly over the last thirty years. Studies have shown associations between environmental factors and the brain’s ability to encode, store and retrieve information. Experts now understand how sleep, exercise, diet, botanical medicine and stress management can improve and protect memory.

Sleep

Sufficient sleep before and after learning is an essential element in committing new information to memory. In 2007, Harvard researchers examined the effects of sleep deprivation after new experiences. The study compared people who got enough sleep the night before learning new information to those who got insufficient sleep. Individuals who didn’t sleep enough had a compromised ability to remember the information they had learned. Even a single night of sleep deprivation caused impairment in the hippocampus, part of the brain’s limbic system that is responsible for encoding information to form new memories.

Physical Exercise

During physical activity, the movement of muscles increases circulation throughout the body. Regular aerobic exercise improves blood flow to the brain and strengthens the cardiovascular system, reducing the risk of deficits in memory and stroke (loss of neurological function following blood loss to the brain).

All physical activity can support a healthy memory, so the best exercise is one that you enjoy and practice often. However, some activities offer benefits besides better memory. Researchers at the McGill University in Montreal studied the health effects of tango dancing on thirty adults between the ages of 68 and 99 years. Half the participants joined a walking program and the other half took lessons for tango, a dance involving a series of complex movements. Both groups improved their scores on memory tests, but the tango dancers also experienced improved self-esteem, balance, coordination and multi-tasking ability.

Mental Exercise

When it comes to memory, mental exercise is as important as physical exercise. Older adults who read, play games, solve puzzles, take classes and learn new things have better memories than those who do not. The more you use your memory, the longer you will enjoy it, so spend at least 10 to 15 minutes every day exercising your brain.

Nutrition

Crucial constituents of brain cells, omega-3 fats like docosahexaenoic acid (DHA) are one of the most important nutrients for memory. Researchers have found that fish, the best source of DHA, is especially good at reducing risk of Alzheimer’s disease and slowing age-related cognitive decline. Many fish are contaminated with mercury and other hazardous pollutants, but in general, species with the lowest levels of toxins and the highest concentrations of DHA include wild salmon, herring, sardines and anchovies. To find the best choices in your area, search the Monterey Bay Aquarium’s Seafood Watch website: www.montereybayaquarium.org/cr/seafoodwatch.aspx. Raw nuts and seeds, including ground flax seed and borage oil, are good sources of omega-3 fats, but they do not contain DHA.

Other nutrients also play key roles in preserving memory. Antioxidants like vitamins C and E protect brain cells against damage from free radicals (reactive oxygen molecules). Studies have shown that flavonoids and polyphenols found in berries can prevent and reverse age-related cognitive decline. B vitamins are necessary for the production of neurotransmitters (chemical messengers in the brain) and myelin (a sheath around brain cells that facilitates cell-to-cell communication). B vitamins are also required for the to body eliminate homocysteine. This amino acid has been linked to Alzheimer’s disease and stroke (common causes of memory loss), as well as heart attack.

Colorful fruits and vegetables are the best source of these necessary nutrients. Choices that are especially good for brain health include blueberries, blackberries, black currants, strawberries, beans, peas, citrus fruit, spinach, kale, and dark green leafy vegetables like dandelion, mustard, beet, collard and turnip greens.

Botanical Medicine

Ginkgo biloba has been used as a medicine for thousands of years and studies have confirmed its cardiovascular benefits. In individuals with compromised circulation, it can improve memory by increasing blood flow to the brain. Evidence has shown that it can also slow certain types of dementia involving memory loss. In 2005, researchers in Poland studied twenty-seven adults with dementia related to Alzheimer’s disease, vascular dementia, or both. They were given Ginkgo extract for six months. The herb was well-tolerated and none of the participants showed loss of cognitive function.

Gingko biloba can increase the risk of bleeding, interfere with some medications, and at high doses, cause side effects like gastrointestinal upset and headaches. Individuals interested in taking Ginkgo should seek guidance from a doctor trained in botanical medicine.

Stress Management

Stress can have a negative affect on memory. Elevated levels of adrenal stress hormones called glucocorticoids can damage the memory center of the brain, the hippocampus. All cells need glucose to function, including brain cells responsible for memory. Glucocorticoids can inhibit the transport of glucose into hippocampal memory neurons. In 1991, researchers at Stanford University found that memory can be affected when stress hormones are elevated for four hours or longer.

Some acute stress is good, like preparing for an important speech or running a race. But when stress is chronic, it increases the risk of high blood pressure and cardiovascular disease, conditions that can lead to stoke and memory loss. Managing stress can be an important part of preserving memory and several effective options exist: exercise, yoga, meditation, breathing exercises, progressive muscle relaxation, and qi gong, among others.

Other Factors

While memory loss may be a normal part of aging, it may also be related to other factors, like Alzheimer’s disease, stroke, infection, head trauma or alcoholism. Individuals affected by these conditions, and those who suspect they may be, should talk to their doctors about treatment. These underlying causes of illness must be addressed before memory loss can improve.

REFERENCES

Bidzan L et al. [Preliminary assessment of ginkgo biloba (Ginkofar) in patients with dementia]. Psychiatr Pol. 2005 May-Jun;39(3):559-66.

Farooqui T and Farooqui AA. Aging: an important factor for the pathogenesis of neurodegenerative diseases. Mech Ageing Dev. 2009 Apr;130(4):203-15. Epub 2008 Nov 21.

McKinley P et al. Effect of a community-based Argentine tango dance program on functional balance and confidence in older adults. J Aging Phys Act. 2008 Oct;16(4):435-53.

Virgin CE Jr et al. Glucocorticoids inhibit glucose transport and glutamate uptake in hippocampal astrocytes: implications for glucocorticoid neurotoxicity. J Neurochem. 1991 Oct;57(4):1422-8.

Yoo SS et al. A deficit in the ability to form new human memories without sleep. Nat Neurosci. 2007 Mar;10(3):385-92. Epub 2007 Feb 11.

Multi-Vitamin-Mineral Supplements

Multi-vitamin-mineral formulas are the most popular nutritional supplements in the United States and experts estimate that up to half of all adults take them regularly. But studies have shown mixed results and consumers are concerned. Are they necessary? Are they safe? Who should take them? Are liquids better than capsules? Which brands are best? The following guide will answer these questions and more.

Foods First

Taking nutritional supplements is never a substitute for eating whole foods. Fruits and vegetables are the best sources of the vitamins and minerals our bodies need and most adults should eat seven to nine servings each day. (One serving of fruits and vegetables is one half cup, excluding raw leafy greens like lettuce, which require one cup per serving.)

Two exceptions exist: vitamins B12 and D are found primarily in animal products. Vitamin D is also found in small amounts in mushrooms and sunshine stimulates its production in the skin. Vitamin B12 can be found in trace amounts in sea vegetables and microalgaes but lab tests have shown that this form does not have the same activity as vitamin B12 from animal sources.

Comparing apples to apples and oranges to oranges, some are more nutritious than others. Foods grown in nutrient-rich soils are rich in nutrients and foods grown in nutrient-poor soils are poor in nutrients. After all, plants cannot absorb what is not in the soil. Nutrient depletion largely results from the use of chemical fertilizers that replenish only three of the many nutrients plants need to thrive. But farmers who use natural fertilizers, grow a variety of plants and rotate their crops actually enrich and improve the soil. Find these farmers and their nutritious fruits and vegetables at your local farmers’ market or join their CSA (community-supported agriculture).

Another benefit of produce from local farms is fresher food. Because fruits and vegetables begin to lose nutrients as soon as they are picked, those that travel hundreds or thousands of miles between farm and plate usually contain less vitamins than their freshly picked counterparts. Healthy adults eating plenty of local, fresh-picked fruits and vegetables – and those preserved at peak ripeness – and a minimal amount of animal products probably do not need to take a daily multi-vitamin-mineral supplement (MVMS).

Special Needs

For some, MVMS can provide extra insurance that nutritional needs are being met. People who benefit most include adults who do not eat at least seven servings of fruits and vegetables each day, growing children, couples who plan to conceive, pregnant and lactating women, and older adults whose ability to assimilate nutrients becomes less efficient with age. Individuals following a vegan diet should supplement as well because they are more likely to be deficient in vitamins B12 and D (depending on sun exposure). Individuals with increased needs for nutrients due to chronic medical conditions or prescription medications also benefit. Blood tests can measure levels of vitamins and minerals to determine if supplementation is necessary, and they can also be used to track progress after supplementation.

MVMS are not standardized and different products contain different combinations and concentrations of vitamins and minerals. People with special nutritional needs should ask their doctor for recommendations to ensure they are getting exactly what their bodies require.

Favored Forms

MVMS come in many forms: tablets, chewable tablets, capsules, gel capsules and liquids. Tablets can hold more ingredients but may also contain more fillers and binders to keep everything together. Some companies use animal-derived gelatin to encapsulate their formulas, so individuals avoiding animal products should seek supplements with cellulose capsules. For individuals with compromised gastrointestinal function, liquids and gel capsules are often easier to digest and absorb. Liquids, however, usually need to be refrigerated and may have shorter shelf lives.

Minerals are sometimes chelated (bound to an amino acid) to increase absorption. Because chelated minerals take up much more volume than minerals alone, MVM formulas containing chelates often require a larger daily dose, up to eight capsules per day. Forms most easily absorbed include aspartates, citrates, malates and picolinates.

Extra Ingredients

In addition to vitamins and minerals, some MVMS may contain ingredients like omega-3 fatty acids, probiotics (healthy intestinal bacteria), green tea and other herbs. These can be helpful for some people, but not for others. For example, many diets are deficient in omega-3 fats and could benefit from supplementation, but fatty acids found in fish oil can interfere with certain medications and high doses may increase the risk of bleeding in some individuals. Green tea is a powerful antioxidant and has been studied for its protective effects against cancer and other illnesses, but it also contains caffeine that can aggravate certain conditions like ulcers, anxiety and insomnia. Herbal medicines, including those added to MVMS, should only be taken under the guidance of a doctor trained in their use.

Other ingredients may be used in the manufacturing process, like fillers and binders, or added to improve flavor, appearance and palatability (especially in chewable and liquid products). Always read the list of additional ingredients on the label and avoid supplements containing sweeteners, colors and artificial flavors. Sensitive or allergic individuals should check for gluten, dairy, yeast, corn, soy or shellfish.

Careful Consumption

Because MVMS contain nutrients that require fat for absorption, like calcium and vitamins A, E and D, they should always be taken with food. Food stimulates the secretion of stomach acids, so taking these supplements at mealtimes can also improve the digestion and absorption of nutrients. If you can, spread the dose throughout the day unless directed otherwise.

Safety Questions

Because dietary supplements are regarded as food, the United States Food and Drug Administration does not have standards for testing and manufacturers are responsible for determining that the ingredients they use are safe. Consumer Lab, an independent company that tests supplements for safety, found problems with more than 30 percent of products they recently tested. Some MVMS contained too much of some nutrients, too little of others or dangerous ingredients like lead.

Recent Research

Earlier this year, the Archives of Internal Medicine published a study using data from the Women’s Health Initiative to evaluate potential benefits of supplementation in postmenopausal women. After investigating their use of MVMS, researchers found that the supplements made little or no difference in the women’s risk for common cancers, cardiovascular disease or death. However, there were no standards set for quality or consumption of MVMS and because the women were taking not all taking the same supplement, variations existed in the potency of the formulas and the frequency of their use. Benefits of MVMS cannot be dismissed by studies such as this.

Quality Concerns

High quality MVMS may be expensive, but price isn’t always an indicator of quality. When selecting supplements, choose products that list important information on the label: expiration date, lot or batch number, name and address of the manufacturer, and the scientific name, quantity and part (root, leaf, flower) of any plant ingredient. To ensure that products have been tested by an independent lab and found to contain the ingredients listed on the label, look for brands with seals from Consumer Lab, the United States Pharmacopeia (USP), the National Nutritional Foods Association (NNFA) or National Sanitation Foundation (NSF) International. But keep in mind that such certification does not guarantee the manufacturers started with high quality raw ingredients or tested the supplements in clinical trials. Direct questions like these to the manufacturer or ask a knowledgeable practitioner to recommend reputable brands.

Cooking With Kids

Good nutrition is important for everybody, but it is especially essential for children during their years of growth and development. Unfortunately, kids can be picky eaters and they aren’t always interested in eating vegetables or trying new foods. But sharing the kitchen may make a difference. In a 2008 research study at Columbia University, children involved in meal preparation were more likely to try new foods, enjoy the foods they cooked, and eat those foods again in the future. If they’re not in the kitchen yet, follow these simple steps to get your kids cooking.

Assign Appropriate Tasks

Adults should always perform or supervise steps involving stovetops and sharp edges, but there are plenty of tasks well suited to young cooks. After they wash their hands with warm, soapy water, children can wash produce and scrub vegetables with a brush. They can measure ingredients and help with stirring, mixing, whisking, mashing and tossing. Kids can use salad spinners and timers. They can peel citrus fruit and assemble fruit kebobs. Those too young to handle knives can use scissors to cut green leafy vegetables and herbs like lettuce, chard, kale, basil and sage. Older children can also help keep the kitchen clean by wiping counters, washing and drying dishes.

Shop Together

Children are more likely to try new foods they pick out themselves, so take your kids to the farmers’ market and the grocery store. Let them pick out fruits, vegetables, beans and whole grains they are interested in eating or cooking. If you don’t know how to cook something your child selects, look it up and learn how to prepare it together. If you have a garden, involve your kids in the process, from planting seeds and tending plants to harvesting and cooking what you grow.

Engage the Senses

When planning meals with kids in mind, aim to engage their senses with a variety of aromas, colors, tastes and textures. Everyone should eat a rainbow of fruits and vegetables every day – red, orange, yellow, green, purple – and kids can have fun keeping track. Use color and texture to introduce new tastes. For example, a child who likes pureed peas may also like pureed spinach or other green foods.

Add Healthy Fat

Fat is an important nutrient and we cannot live without it. It is necessary for the absorption of fat-soluble vitamins in foods, including vitamins A and E in fruits and vegetables. Additionally, fat carries flavor and can make foods that kids usually find unappealing more attractive. Toss steamed vegetables with a little bit of organic butter. Grate some aged Parmesan cheese over roasted vegetables. Drizzle salads with extra virgin olive oil or incorporate it into dressings and vinaigrettes. Spread almond butter on apple slices or use it as a dip for celery and carrot sticks. Or let kids dip pieces of fruit into organic whole milk plain yogurt mixed with a few drops of honey.

Appoint a Salad Maker

Making salads is a great job for kids. They can wash produce, tear lettuce leaves, use a scissors to cut chives and scallions, toss everything together and sprinkle raw nuts and seeds on top. Teach them to make their own vinaigrette by adding extra virgin olive oil, vinegar, Dijon mustard, sea salt and pepper to a clean glass jar and shaking it up until all of the ingredients are thoroughly combined. Assigning salad duty to a willing child will not only ensure that a healthy serving of vegetables will be part of every meal, but it can also make young cooks more enthusiastic about eating greens and allow them to exercise their creativity.

Offer Variety

Because food preferences in children are shaped by what their parents and caregivers make available, especially before the age of four, they should be exposed to a wide variety of whole foods. Unless kids have food allergies, their diet should include fruits, vegetables, whole grains, beans, raw nuts and seeds, nontoxic fish and seafood, and pasture-raised meat and animal products like eggs, milk, yogurt and cheese. To find nontoxic fish and seafood, search by species or geographical location on the website of the Monterey Bay Aquarium’s Seafood Watch Program: http://www.montereybayaquarium.org/cr/seafoodwatch.aspx.

Don’t Negotiate

Unless children have a medical or religious reason to avoid certain foods, don’t offer to make extra dishes to satisfy picky eaters. Parents and caregivers should decide which foods children eat and children should decide how much they eat, given the choices they have. Only offer healthy foods, and if kids are hungry, they will eat.

Be Patient

Encourage your children to try new things, but don’t force them to eat what they don’t want. Even if a child doesn’t like or doesn’t want to try a food, continue to offer it. Be patient because it may require several attempts, a dozen or more, before children become interested in trying new foods. Forcing kids to eat things they don’t like can make matters worse, creating negative associations that cause them to continue avoiding the foods. Instead, help them learn to cook things that are unfamiliar or unappealing so they will be more willing to try them.

Set a Good Example

Kids can be curious creatures. If they see their parents and caregivers consistently cooking and eating a wide variety of healthy whole foods, chances are that eventually they will want to try those foods too. But if children see their parents eating processed foods and snacks, like cookies and potato chips, those are the foods they will ask for. So skip the junk food and be a good role model.